Description

Cyclopenta[B]Pyrrole-2-Carboxylic Acid, 1,2,3,3A,4,6A-Hexahydro-, (2Alpha,3Aalpha,6Aalpha)- (9Ci) is a complex, stereochemically defined heterocyclic carboxylic acid building block. This compound matters as a high-value synthetic intermediate for advanced research and development, particularly in the pharmaceutical sector. It is primarily needed by medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where its unique fused ring system is critical.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of novel herbicides and pesticides with specific stereochemical activity.
• Organic Synthesis: Serves as a versatile precursor for constructing complex polycyclic frameworks in academic and industrial research.
• Ligand and Catalyst Development: The carboxylic acid and heterocyclic structure make it suitable for designing novel chiral ligands for asymmetric catalysis.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors or advanced polymers with specific electronic properties.

Basic Information

Product Name	Cyclopenta[B]Pyrrole-2-Carboxylic Acid, 1,2,3,3A,4,6A-Hexahydro-, (2Alpha,3Aalpha,6Aalpha)- (9Ci)
CAS No.	114613-94-4
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	(2α,3aα,6aα)-1,2,3,3a,4,6a-Hexahydrocyclopenta[b]pyrrole-2-carboxylic acid; Hexahydrocyclopenta[b]pyrrole-2-carboxylic acid; (2Alpha,3Aalpha,6Aalpha)-Hexahydrocyclopenta[B]Pyrrole-2-Carboxylic Acid; 1,2,3,3a,4,6a-Hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acid; (2R,3aR,6aS)-Octahydrocyclopenta[b]pyrrole-2-carboxylic acid (enantiomer); Fused pyrrolidine-carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our high-purity Cyclopenta[B]Pyrrole-2-Carboxylic Acid derivative is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is sensitive to strong acids and organic solvents; keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.