Description

(E)-4-Bromo-1-Chloro-2-Methyl-2-Butene is a high-purity halogenated alkene building block, essential for advanced organic synthesis. Its unique structure, featuring both bromine and chlorine leaving groups on a methyl-substituted butene backbone, makes it a versatile intermediate for constructing complex molecular architectures. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of novel therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, leveraging its reactivity to create complex heterocyclic structures.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions to introduce functionalized alkyl chains.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing specialized ligands used in asymmetric catalysis and organometallic chemistry.
• Chemical Biology Probes: Utilized in the creation of molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	(E)-4-Bromo-1-Chloro-2-Methyl-2-Butene
CAS No.	114506-04-6
Molecular Formula	C5H8BrCl
Molecular Weight	183.47 g/mol
Synonyms	1-Chloro-4-bromo-2-methyl-2-butene (E); trans-4-Bromo-1-chloro-2-methyl-2-butene; 2-Butene, 4-bromo-1-chloro-2-methyl-, (E)-; 4-Bromo-1-chloro-2-methyl-2-butene; (E)-1-Chloro-4-bromo-2-methyl-2-butene; Halogenated C5 Alkene Intermediate; Bromochloromethylbutene
EINECS	Contact for details

Quality Control

Our (E)-4-Bromo-1-Chloro-2-Methyl-2-Butene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, containers should be amber glass or opaque. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Isomeric Purity (E-isomer)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.