Description

2H-Isoindole-2-Acetic Acid, 1,3-Dihydro--α--Hydroxy-1,3-Dioxo- is a specialized heterocyclic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique isoindole core structure makes it a valuable precursor for developing novel pharmaceuticals and functional materials. This high-purity intermediate is essential for research and production in fine chemical and life science industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides due to its bioactive heterocyclic scaffold.
• Material Science: Building block for creating organic semiconductors, dyes, and photoactive polymers.
• Academic & R&D: Essential reagent for medicinal chemistry research, library synthesis, and exploring new chemical entities in university and corporate labs.
• Peptidomimetics: Serves as a constrained scaffold in the design of peptide mimics for drug discovery programs.

Basic Information

Product Name	2H-Isoindole-2-Acetic Acid, 1,3-Dihydro--α--Hydroxy-1,3-Dioxo-
CAS No.	114505-80-5
Molecular Formula	C10H7NO5
Molecular Weight	221.17 g/mol
Synonyms	1,3-Dihydro-α-hydroxy-1,3-dioxo-2H-isoindole-2-acetic acid; 2-(Carboxymethyl)-1,3-dihydroxyisoindole-1,3-dione; α-Hydroxy-1,3-dioxo-1,3-dihydro-2H-isoindole-2-acetic acid; Hydroxydioxoisoindoleacetic acid; Isoindole-2-acetic acid derivative; 1,3-Dihydroxyisoindole-2-acetic acid 1,3-dione; 114505-80-5; 2H-Isoindole-2-acetic acid, 1,3-dihydro-α-hydroxy-1,3-dioxo-
EINECS	Contact for details

Quality Control

Our 2H-Isoindole-2-Acetic Acid, 1,3-Dihydro--α--Hydroxy-1,3-Dioxo- is manufactured under a strict quality management system. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.