Description

4’-Methyl-D3-Acetophenone CAS NO 114379-92-9 is a deuterium-labeled isotopologue of 4-methylacetophenone, where three hydrogen atoms are replaced by deuterium at the methyl group of the acetyl moiety. This stable isotope-labeled compound is essential for applications requiring precise internal standards in quantitative mass spectrometry, ensuring accurate and reliable analytical results. It is primarily needed by research institutions, pharmaceutical companies, and analytical laboratories involved in drug metabolism studies (DMPK), proteomics, and environmental analysis.

Application

• Internal Standard for Quantitative Mass Spectrometry (LC-MS/MS, GC-MS)
• Deuterated Standard in Pharmaceutical Research & Drug Metabolism (DMPK/PK studies)
• Tracer Compound in Metabolic Pathway Analysis and Proteomics
• Reference Material for Analytical Method Development and Validation
• Isotope Dilution Analysis in Environmental Testing
• High-Purity Chemical Standard for Quality Control Laboratories

Basic Information

Product Name	4’-Methyl-D3-Acetophenone
CAS No.	114379-92-9
Molecular Formula	C9H7D3O
Molecular Weight	137.20 g/mol
Synonyms	1-(4-Methylphenyl)ethanone-d3; 4-Methylacetophenone-d3; p-Methylacetophenone-d3; 4-Acetyltoluene-d3; 4'-Methylacetophenone-d3; Methyl-d3 4-Methylphenyl Ketone; [D3]-4'-Methylacetophenone; p-Methyl-D3-acetophenone
EINECS	Contact for details

Quality Control

Our 4’-Methyl-D3-Acetophenone is manufactured under strict quality systems to ensure high isotopic purity and chemical integrity, critical for its role as an analytical standard. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (D-atom %), chemical purity, and identity confirmation. We adhere to relevant standards for high-purity reference materials to guarantee reliable and reproducible performance in sensitive analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use to prevent evaporation and potential concentration changes.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC / GC)	≥ 98.0%
Isotopic Purity (D-atom %)	≥ 98.0% (by MS)
Isotopic Enrichment	≥ 99.0% at labeled positions
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.