Description

2-Methyl-5-Trifluoromethoxybenzimidazole is a high-value, fluorinated benzimidazole derivative, a key heterocyclic building block prized for its unique electronic and steric properties imparted by the trifluoromethoxy substituent. This compound is essential for advanced research and development in life sciences, enabling the synthesis of novel molecules with enhanced biological activity and metabolic stability. It is primarily sought by pharmaceutical, agrochemical, and specialty chemical manufacturers for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of novel drug candidates, particularly in antiviral, anticancer, and anti-inflammatory research pipelines.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethoxy group can improve lipophilicity and target binding.
• Ligand & Catalyst Development: Serves as a precursor for nitrogen-containing ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials and advanced polymers due to its electron-withdrawing characteristics.
• Chemical Biology Probes: Useful for designing molecular probes and inhibitors to study enzyme function and biological pathways.

Basic Information

Product Name	2-Methyl-5-Trifluoromethoxybenzimidazole
CAS No.	114164-97-5
Molecular Formula	C9H7F3N2O
Molecular Weight	216.16 g/mol
Synonyms	5-(Trifluoromethoxy)-2-methyl-1H-benzimidazole; 2-Methyl-5-(trifluoromethoxy)-1H-benzimidazole; 1H-Benzimidazole, 2-methyl-5-(trifluoromethoxy)-; 2-Methyl-5-trifluoromethoxybenzimidazole; 2-Methyl-5-(trifluoromethoxy)benzimidazole
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our chemical intermediates. Production of 2-Methyl-5-Trifluoromethoxybenzimidazole adheres to current Good Manufacturing Practices (cGMP) where applicable, ensuring batch-to-batch consistency and traceability. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.