Description

(trans-2-(p-Tolyl)Cyclopropyl)Methanol is a specialized chiral building block featuring a cyclopropane ring substituted with a p-tolyl group and a hydroxymethyl moiety. This compound matters as a high-value intermediate for the synthesis of complex molecules, offering a rigid, three-dimensional structure that can influence biological activity and material properties. It is needed by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the cyclopropane ring can enhance stability and bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Building block for novel polymers or liquid crystals, leveraging its rigid, aromatic structure.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific synthetic projects requiring this unique scaffold.

Basic Information

Product Name	(trans-2-(p-Tolyl)Cyclopropyl)Methanol
CAS No.	114095-61-3
Molecular Formula	C11H14O
Molecular Weight	162.23 g/mol
Synonyms	trans-2-(4-Methylphenyl)cyclopropanemethanol; (1R,2S)-rel-2-(4-Methylphenyl)cyclopropanemethanol; p-Tolylcyclopropylmethanol; 2-(p-Tolyl)cyclopropylmethanol; 2-(4-Methylphenyl)cyclopropanemethanol; (trans-2-(4-Methylphenyl)cyclopropyl)methanol; (2R,1'S)-2-(4-Methylphenyl)cyclopropanemethanol (enantiomer); [1,1'-Bi(cyclopropane)]-2-methanol, 2'-(4-methylphenyl)-
EINECS	Contact for details

Quality Control

Our (trans-2-(p-Tolyl)Cyclopropyl)Methanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided to guarantee consistent quality, identity, and purity for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (trans-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.