Description

trans-2-(3-Methoxyphenyl)Cyclopropyl)Methanol is a specialized chiral building block featuring a cyclopropane ring substituted with a methoxyphenyl group and a hydroxymethyl moiety. This compound is valued for its rigid, three-dimensional structure, which is crucial for modulating the biological activity and physicochemical properties of advanced pharmaceutical intermediates. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, particularly those targeting central nervous system disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for neurological and psychiatric applications.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where the cyclopropane scaffold contributes to enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for designing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific optical or mechanical properties.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function and receptor interactions.

Basic Information

Item	Detail
Product Name	trans-2-(3-Methoxyphenyl)Cyclopropyl)Methanol
CAS No.	114095-60-2
Molecular Formula	C11H14O2
Molecular Weight	178.23 g/mol
Synonyms	trans-2-(3-Methoxyphenyl)cyclopropanemethanol; (1R,2S)-rel-2-(3-Methoxyphenyl)cyclopropanemethanol; 2-(3-Methoxyphenyl)cyclopropylmethanol; (trans)-2-(m-Methoxyphenyl)cyclopropylmethanol; 3-Methoxy-trans-2-phenylcyclopropanemethanol; (1R,2S)-2-(3-Methoxyphenyl)cyclopropane-1-methanol; A Chiral Cyclopropane Building Block
EINECS	Contact for details

Quality Control

Our trans-2-(3-Methoxyphenyl)Cyclopropyl)Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (trans isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.