Description

tert-Butyl(4-Fluorophenoxy)Dimethylsilane is a specialized organosilicon compound featuring a fluorinated phenoxy group. This compound serves as a valuable silylating agent and protected intermediate in advanced organic synthesis, offering unique reactivity for introducing silicon-protected functionalities. It is primarily utilized by pharmaceutical, agrochemical, and advanced materials researchers for constructing complex molecular architectures where precise control over functional group protection is critical.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing protected phenol or silane groups.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides that require fluorinated aromatic components.
• Material Science: Precursor for surface modification, creation of silane coupling agents, and development of specialty polymers and resins.
• Organic Synthesis Reagent: Acts as a protecting group for phenols or as a silylating agent in multi-step synthetic routes under mild conditions.
• Liquid Crystal & OLED Research: Intermediate in the synthesis of fluorinated aromatic compounds for electronic and optoelectronic materials.
• Cross-Coupling Reactions: Used in palladium-catalyzed reactions like Suzuki or Stille couplings to construct biaryl systems.

Basic Information

Product Name	tert-Butyl(4-Fluorophenoxy)Dimethylsilane
CAS No.	113984-68-2
Molecular Formula	C12H19FOSi
Molecular Weight	226.36 g/mol
Synonyms	tert-Butyldimethyl(4-fluorophenoxy)silane; 4-Fluorophenoxy-tert-butyldimethylsilane; (4-Fluorophenoxy)(tert-butyl)dimethylsilane; DTXSID00676450; TBDMS 4-fluorophenyl ether; Silane, tert-butyl(4-fluorophenoxy)dimethyl-; AKOS005258890
EINECS	Contact for details

Quality Control

Our tert-Butyl(4-Fluorophenoxy)Dimethylsilane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, GC, NMR, and FTIR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP and ISO 9001 standards where applicable, ensuring reliability for your most demanding synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (nitrogen or argon) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.480 - 1.490
Density (g/mL at 25°C)	0.98 - 1.02

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.