Description

Andrographidine E is a bioactive diterpenoid lactone compound isolated from the medicinal plant *Andrographis paniculata*. This high-purity phytochemical is valued for its role as a key reference standard and active pharmaceutical ingredient (API) in advanced research and development. It is primarily sought by manufacturers and research institutions in the pharmaceutical, nutraceutical, and phytochemical sectors for applications in metabolic and inflammatory pathway studies.

Application

• Pharmaceutical research as a reference standard for analytical method development and quality control.
• Development of herbal supplements and nutraceutical formulations targeting immune system support.
• Pre-clinical studies investigating potential anti-inflammatory and metabolic modulatory activities.
• Isolation and purification processes for the production of high-value phytochemical extracts.
• Academic and industrial research into the structure-activity relationships of diterpenoids.
• As a critical raw material in the synthesis of more complex semi-synthetic derivatives for drug discovery.

Basic Information

Product Name	Andrographidine E
CAS No.	113963-41-0
Molecular Formula	C₂₀H₃₀O₅
Molecular Weight	350.45 g/mol
Synonyms	Andrographidine E; 14-Deoxy-11,12-didehydroandrographolide; 3-[2-[Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone; Andrographolide derivative; 14-Deoxy-11,12-didehydroandrographiside; (5R,6R,8aS)-6-[1-[(E)-2-(4-Hydroxy-5-oxo-2,5-dihydrofuran-3-ylidene)ethyl]-2-methylidene-5-methyloctahydronaphthalen-1-yl]-2-methylhept-5-en-2-ol (IUPAC)
EINECS	Contact for details

Quality Control

Every batch of Andrographidine E is produced and tested under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing comprehensive analytical results, including HPLC purity, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥95.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.