Description

Tematropium CAS NO 113932-41-5 is a high-purity pharmaceutical intermediate and active ingredient of significant importance in modern medicinal chemistry. Its primary value lies in its role as a key building block for the synthesis of advanced therapeutic agents, particularly in the respiratory and neurological fields. This compound is essential for research institutions, pharmaceutical development laboratories, and large-scale API manufacturers seeking reliable, high-quality raw materials for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex active pharmaceutical ingredients (APIs).
• Respiratory Drug Development: Used in research and production of novel bronchodilators and anticholinergic agents for treating COPD and asthma.
• Neurological Research: Acts as a key synthon in the development of compounds targeting muscarinic receptors for potential neurological applications.
• Process Chemistry & Scale-Up: Employed in process optimization and kilogram-to-ton scale manufacturing under GMP guidelines.
• Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control testing.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Tematropium
CAS No.	113932-41-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Tematropium; 113932-41-5; (1R,2R,4S,5S,7s)-9-(2-Hydroxy-2,2-dithien-2-ylacetyl)oxy-9-methyl-3-oxa-9-azoniatricyclo[3.3.1.0²,⁴]nonane; 3-[(Hydroxydi-2-thienylacetyl)oxy]-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane; Tropane derivative, Tematropium.
EINECS	Contact for details

Quality Control

Our Tematropium is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC for assay and impurity profiling, to meet the stringent requirements of pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and residual solvent levels is provided with each shipment to support your regulatory and quality documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.