Description

D-Cysteine, S-2-Pyridinyl- (9Ci) is a specialized, non-proteinogenic amino acid derivative featuring a chiral D-configuration and a pyridinylthioether side chain. This unique structure makes it a valuable chiral building block and ligand for advanced pharmaceutical research and asymmetric synthesis. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors. The compound is supplied under stringent quality control to ensure batch-to-batch consistency for critical applications.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system.
• Asymmetric Catalyst Ligand: Used as a precursor or direct ligand in the synthesis of chiral catalysts for enantioselective transformations in fine chemical manufacturing.
• Biochemical Research: Employed in proteomics and enzymology studies to investigate enzyme mechanisms, protein folding, and metal-binding sites due to its modified cysteine structure.
• Peptide Synthesis: Acts as a protected or modified cysteine analog in the solid-phase synthesis of specialized peptides with enhanced stability or specific binding properties.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.
• Material Science: Investigated for the development of functionalized surfaces and bio-conjugates in advanced material applications.

Basic Information

Product Name	D-Cysteine, S-2-Pyridinyl- (9Ci)
CAS No.	113828-61-8
Molecular Formula	C8H10N2O2S
Molecular Weight	198.24 g/mol
Synonyms	D-2-Amino-3-((pyridin-2-yl)thio)propanoic acid; (R)-2-Amino-3-(pyridin-2-yldisulfanyl)propanoic acid; S-(2-Pyridinyl)-D-cysteine; D-Cysteine S-(2-pyridyl) ether; (R)-3-((Pyridin-2-yl)thio)alanine; 113828-61-8; D-3-(2-Pyridyldithio)alanine
EINECS	Contact for details

Quality Control

Our D-Cysteine, S-2-Pyridinyl- (9Ci) is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets the high standards required for research and development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We can support development with custom purity grades, including materials suitable for use under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (D-isomer)
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.