Description

2-(1,2-Dimethyl-1H-Indol-3-Yl)Ethanamine Hydrochloride is a high-purity organic salt derivative of a substituted indole, valued for its role as a critical synthetic intermediate in advanced pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel therapeutic agents, particularly within the central nervous system (CNS) and oncology domains. Its defined structure and purity make it a reliable building block for constructing complex molecular architectures in a controlled and scalable manner.

Application

This specialized chemical intermediate serves key functions in several high-value industrial and research sectors:

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological receptors and signaling pathways.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization studies for structure-activity relationship (SAR) analysis.
• Biochemical Tool Compound: Employed in the development of receptor ligands and probes for pharmacological and biological assays.
• Process Chemistry & Scale-Up: Serves as a defined starting material for the development and optimization of Good Manufacturing Practice (GMP) synthetic routes.
• Academic & Institutional Research: Utilized in universities and research institutes for exploratory organic synthesis and the study of heterocyclic chemistry.
• Contract Research & Manufacturing (CRO/CMO): A supplied raw material for organizations providing custom synthesis and development services.

Basic Information

Product Name	2-(1,2-Dimethyl-1H-Indol-3-Yl)Ethanamine Hydrochloride
CAS No.	113772-31-9
Molecular Formula	C13H19ClN2
Molecular Weight	238.76 g/mol
Synonyms	2-(1,2-Dimethyl-1H-indol-3-yl)ethan-1-amine hydrochloride; 1,2-Dimethyl-3-(2-aminoethyl)indole hydrochloride; 3-(2-Aminoethyl)-1,2-dimethylindole hydrochloride; 2-(1,2-Dimethylindol-3-yl)ethylamine hydrochloride; 1,2-Dimethyltryptamine hydrochloride (1,2-DMT hydrochloride); 2-(1,2-Dimethyl-1H-indol-3-yl)ethanamine HCl; 113772-31-9; α-Methyltryptamine derivative hydrochloride
EINECS	Contact for details

Quality Control

Our production of 2-(1,2-Dimethyl-1H-Indol-3-Yl)Ethanamine Hydrochloride adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements, supporting development under quality-by-design (QbD) principles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.