Description

2-Amino-1-(4-Methoxybenzyl)-4,5,6,7-Tetrahydro-1H-Indole-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique indole-based heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities. Pharmaceutical R&D teams and fine chemical manufacturers need it to develop new therapeutic agents, particularly in central nervous system (CNS) and oncology research, where its molecular framework is highly valuable.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for designing and synthesizing novel compounds for biological screening and structure-activity relationship (SAR) studies.
• CNS Drug Development: Used in the research and development of potential therapeutics targeting neurological disorders, leveraging the indole core's relevance to neuroactive compounds.
• Oncology Research: Employed as a building block for creating novel molecules evaluated for anti-cancer properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and process development projects.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	2-Amino-1-(4-Methoxybenzyl)-4,5,6,7-Tetrahydro-1H-Indole-3-Carbonitrile
CAS No.	113772-12-6
Molecular Formula	C17H19N3O
Molecular Weight	281.35 g/mol
Synonyms	2-Amino-1-[(4-methoxyphenyl)methyl]-4,5,6,7-tetrahydro-1H-indole-3-carbonitrile; 1-(4-Methoxybenzyl)-2-amino-4,5,6,7-tetrahydro-1H-indole-3-carbonitrile; 2-Amino-1-(4-methoxybenzyl)-4,5,6,7-tetrahydroindole-3-carbonitrile; 113772-12-6; 2-Amino-1-(p-methoxybenzyl)-4,5,6,7-tetrahydro-1H-indole-3-carbonitrile; 1H-Indole-3-carbonitrile, 2-amino-1-[(4-methoxyphenyl)methyl]-4,5,6,7-tetrahydro-
EINECS	Contact for details

Quality Control

Our 2-Amino-1-(4-Methoxybenzyl)-4,5,6,7-Tetrahydro-1H-Indole-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.