Description

4-Thiazoleacetonitrile, α-Hydroxy-2-Methyl- is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), novel crop protection agents, and other fine chemicals where the thiazole moiety is a critical structural feature.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly those targeting infectious diseases or metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole ring.
• Chemical Research & Development: Acts as a versatile synthon for constructing complex heterocyclic systems in academic and industrial R&D settings.
• Material Science Precursor: Potential use in the synthesis of organic ligands for catalysts or functional materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	4-Thiazoleacetonitrile, α-Hydroxy-2-Methyl-
CAS No.	113732-63-1
Molecular Formula	C6H6N2OS
Molecular Weight	154.19 g/mol
Synonyms	2-Methyl-α-hydroxy-4-thiazoleacetonitrile; (2-Hydroxy-1-(4-thiazolyl)ethyl)cyanide; α-Hydroxy-2-methyl-4-thiazoleacetonitrile; 4-Thiazoleacetonitrile, α-hydroxy-2-methyl-; 1-(4-Thiazolyl)-2-hydroxypropionitrile; 2-Hydroxy-1-(1,3-thiazol-4-yl)propanenitrile
EINECS	Contact for details

Quality Control

Our 4-Thiazoleacetonitrile, α-Hydroxy-2-Methyl- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.