Description

(E)-4-Bromobut-2-En-1-Ol CAS NO 113661-09-9 is a versatile brominated allylic alcohol intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring both a reactive bromine atom and a hydroxyl group on an alkene backbone, makes it a valuable building block for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those requiring stereoselective introduction of functionalized butene chains.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, where the bromo-alkene moiety can be further functionalized.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Monomer: Can be polymerized or incorporated into polymers to impart specific properties, such as cross-linking sites or reactivity.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme mechanisms.

Basic Information

Product Name	(E)-4-Bromobut-2-En-1-Ol
CAS No.	113661-09-9
Molecular Formula	C4H7BrO
Molecular Weight	151.00 g/mol
Synonyms	(E)-4-Bromo-2-buten-1-ol; trans-4-Bromo-2-buten-1-ol; 4-Bromo-2-buten-1-ol, (E)-; 2-Buten-1-ol, 4-bromo-, (E)-; 4-Bromobut-2-en-1-ol; (E)-4-Bromobut-2-enol; 4-Bromo-crotyl alcohol
EINECS	Contact for details

Quality Control

Our (E)-4-Bromobut-2-En-1-Ol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality systems are designed to meet the stringent requirements of GMP and ISO standards for fine chemical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, containers should be amber glass or otherwise opaque.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity ((E)-isomer)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.