Description

Moxidectin CAS NO 113507-06-5 is a potent semi-synthetic macrocyclic lactone belonging to the milbemycin class of compounds. This broad-spectrum endectocide is valued for its high efficacy and long-lasting activity against a wide range of internal and external parasites. It is a critical active pharmaceutical ingredient (API) for manufacturers in the animal health and veterinary pharmaceutical industries. The compound's unique mode of action and favorable safety profile make it a cornerstone in parasite control programs for livestock and companion animals globally.

Application

• Veterinary Pharmaceutical Formulations: Primary use as the active ingredient in injectable, pour-on, oral, and topical solutions for livestock (cattle, sheep) and companion animals (dogs).
• Parasite Control in Livestock: Effective against nematodes (roundworms), arthropods (lice, mites), and certain myiasis-causing flies (screwworm) in cattle and sheep.
• Heartworm Prevention: Key component in monthly preventative medications for dogs, targeting the larval stages of Dirofilaria immitis.
• Companion Animal Dermatology: Treatment of demodectic and sarcoptic mange (scabies) in dogs.
• Research & Development: Used as a reference standard and for the development of new antiparasitic agents and combination therapies.
• Agricultural Pest Management: Investigational use in specific integrated pest management (IPM) programs, subject to regional regulatory approvals.

Basic Information

Product Name	Moxidectin
CAS No.	113507-06-5
Molecular Formula	C37H53NO8
Molecular Weight	639.82 g/mol
Synonyms	Moxidectin; LL-F28249-α; Nemadectin; (2aE,4E,5'S,6R,6'S,7S,8E,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(E)-Ethylidene]-5',6',6'a,7,10,11,14,15,17a,20,20a,20b-dodecahydro-5',6,8,19-tetramethyl-17-oxospiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-[2H]pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-3-O-methyl-α-L-arabino-hexopyranoside; CYDECTIN; EQUEST; PROHEART
EINECS	Contact for details

Quality Control

Our Moxidectin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. Certificates of Analysis (COA) are provided, detailing results for identity, assay, related substances, residual solvents, and microbiological limits. We support compliance with cGMP, VICH guidelines, and relevant pharmacopoeial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water (Karl Fischer)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Microbial Limits	Meets Ph. Eur./USP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.