Description

(1S,4S)-2-Boc-2,5-Diazabicyclo[2.2.1]Heptane CAS NO 113451-59-5 is a high-purity, chiral bicyclic diamine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its role as a protected intermediate for constructing complex molecules with precise stereochemistry, essential for developing active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and catalyst development.

Application

• Pharmaceutical Intermediate: A key chiral scaffold in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Ligand Synthesis: Used to prepare sophisticated chiral ligands for asymmetric catalysis, enhancing the efficiency of stereoselective reactions.
• Peptidomimetic Research: Serves as a constrained diamine backbone in the design of peptide analogs and protease inhibitors.
• Agrochemical Development: Employed in creating chiral active ingredients for herbicides and pesticides with improved efficacy and environmental profiles.
• Academic & Process R&D: A valuable reagent for methodological studies in organic chemistry and scale-up process development.
• Custom Synthesis: A starting point for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	(1S,4S)-2-Boc-2,5-Diazabicyclo[2.2.1]Heptane
CAS No.	113451-59-5
Molecular Formula	C11H20N2O2
Molecular Weight	212.29 g/mol
Synonyms	(1S,4S)-2-(tert-Butoxycarbonyl)-2,5-diazabicyclo[2.2.1]heptane; (1S,4S)-N-Boc-2,5-diazabicyclo[2.2.1]heptane; (1S,4S)-2-Boc-2,5-diazabicyclo[2.2.1]heptane; tert-Butyl (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate; (S,S)-2-Boc-2,5-diazabicyclo[2.2.1]heptane; Boc-DAB-Heptane (S,S); 2,5-Diazabicyclo[2.2.1]heptane-2-carboxylic acid, 1,1-dimethylethyl ester, (1S,4S)-
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Quality Control

Our (1S,4S)-2-Boc-2,5-Diazabicyclo[2.2.1]Heptane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with exacting standards for research and cGMP-grade applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically ≥98%), enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.