Description

Methyl 3-(Cyanomethyl)-1H-Indole-5-Carboxylate is a versatile and high-value indole derivative, serving as a critical advanced pharmaceutical intermediate in modern organic synthesis. Its unique molecular structure, featuring both an ester and a cyanomethyl group on the indole core, makes it an essential building block for constructing complex heterocyclic compounds. This product is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Building block for developing new-generation herbicides and fungicides with novel modes of action.
• Material Science: Used in the research and development of organic semiconductors and advanced functional polymers.
• Academic & R&D: Serves as a standard reagent in university and corporate laboratories for methodological studies in heterocyclic chemistry.
• Dye & Pigment Synthesis: Intermediate for creating specialized indole-based colorants and fluorescent markers.

Basic Information

Product Name	Methyl 3-(Cyanomethyl)-1H-Indole-5-Carboxylate
CAS No.	113438-59-8
Molecular Formula	C12H10N2O2
Molecular Weight	214.22 g/mol
Synonyms	Methyl 3-(cyanomethyl)-1H-indole-5-carboxylate; 1H-Indole-5-carboxylic acid, 3-(cyanomethyl)-, methyl ester; 3-Cyanomethyl-1H-indole-5-carboxylic acid methyl ester; Methyl 3-cyanomethylindole-5-carboxylate; 5-(Methoxycarbonyl)-1H-indole-3-acetonitrile
EINECS	Contact for details

Quality Control

Our production of Methyl 3-(Cyanomethyl)-1H-Indole-5-Carboxylate adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, verified by advanced analytical techniques including HPLC, NMR, and mass spectrometry. We are committed to meeting the exacting standards required for GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.