Description

4-Hydroxy-2-Methyl-4-Phenyl-1,2,3,4-Tetrahydroisoquinoline is a specialized tetrahydroisoquinoline derivative, a key heterocyclic scaffold of significant interest in advanced organic synthesis. This compound matters as a versatile chiral building block and intermediate for the development of complex pharmaceutical molecules and bioactive compounds. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for applications in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly those targeting neurological and cardiovascular pathways.
• Medicinal Chemistry Research: Used as a scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Chiral Synthesis: Employed in asymmetric synthesis due to its stereogenic centers, facilitating the production of enantiomerically pure compounds.
• Agrochemical Development: Acts as an intermediate in the research and synthesis of novel pesticides and herbicides.
• Fine Chemical Production: Utilized in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and catalysis research within university and corporate laboratories.

Basic Information

Product Name	4-Hydroxy-2-Methyl-4-Phenyl-1,2,3,4-Tetrahydroisoquinoline
CAS No.	113258-90-5
Molecular Formula	C₁₆H₁₇NO
Molecular Weight	239.31 g/mol
Synonyms	4-Phenyl-4-hydroxy-2-methyl-1,2,3,4-tetrahydroisoquinoline; 2-Methyl-4-phenyl-1,2,3,4-tetrahydro-4-isoquinolinol; 4-Hydroxy-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline; 4-Phenyl-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-ol; (4RS)-4-Hydroxy-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-2-Methyl-4-Phenyl-1,2,3,4-Tetrahydroisoquinoline is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.