Description

Bicyclo[4.1.0]Hept-2-Ene-7-Carbonitrile, 4-Amino-5-Hydroxy-, (1Alpha,4Beta,5Alpha,6Alpha,7Alpha)- (9Ci) is a high-purity, stereochemically defined bicyclic nitrile derivative with significant synthetic utility. This compound serves as a versatile chiral building block for the development of complex molecules in advanced research and pharmaceutical synthesis. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-infective drug discovery.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its unique bicyclic structure for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products and specialty chemicals requiring precise stereochemical control.
• Academic & Institutional Research: A valuable tool for methodological studies in organic chemistry, including cycloaddition reactions and ring-opening transformations.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and advanced materials with specific functional properties.

Basic Information

Item	Detail
Product Name	Bicyclo[4.1.0]Hept-2-Ene-7-Carbonitrile, 4-Amino-5-Hydroxy-, (1Alpha,4Beta,5Alpha,6Alpha,7Alpha)- (9Ci)
CAS No.	113236-76-3
Molecular Formula	C9H10N2O
Molecular Weight	162.19 g/mol
Synonyms	4-Amino-5-hydroxybicyclo[4.1.0]hept-2-ene-7-carbonitrile; (1α,4β,5α,6α,7α)-4-Amino-5-hydroxybicyclo[4.1.0]hept-2-ene-7-carbonitrile; 7-Cyano-4-amino-5-hydroxybicyclo[4.1.0]hept-2-ene; Bicyclo[4.1.0]hept-2-ene-7-carbonitrile, 4-amino-5-hydroxy-, (1α,4β,5α,6α,7α)-; 113236-76-3; 4-Amino-5-hydroxy-7-cyanobicyclo[4.1.0]hept-2-ene
EINECS	Contact for details

Quality Control

Our production of Bicyclo[4.1.0]Hept-2-Ene-7-Carbonitrile, 4-Amino-5-Hydroxy-, (1Alpha,4Beta,5Alpha,6Alpha,7Alpha)- (9Ci) adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.