Description

3-(5-Methyl-1H-Imidazol-4-Yl)-1-(1-Methyl-1H-Indol-3-Yl)-1-Propanone is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining imidazole and indole moieties. This compound is essential for the research and development of novel therapeutic agents, particularly in the fields of oncology and neurology. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs) targeting specific biological pathways.
• Biochemical Research: Used as a reference standard or precursor in enzymatic studies and receptor binding assays due to its heterocyclic scaffold.
• Medicinal Chemistry: Serves as a core structure for the design and optimization of small molecule libraries for high-throughput screening (HTS) in drug discovery.
• Oncology Research: Investigated for its potential as a precursor in the development of kinase inhibitors and other targeted cancer therapies.
• Neurological Disorder Research: Explored for applications in synthesizing compounds that may interact with central nervous system (CNS) targets.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Item	Detail
Product Name	3-(5-Methyl-1H-Imidazol-4-Yl)-1-(1-Methyl-1H-Indol-3-Yl)-1-Propanone
CAS No.	113140-33-3
Molecular Formula	C16H17N3O
Molecular Weight	267.33 g/mol
Synonyms	1-(1-Methyl-1H-indol-3-yl)-3-(5-methyl-1H-imidazol-4-yl)propan-1-one; 3-(5-Methyl-1H-imidazol-4-yl)-1-(1-methyl-1H-indol-3-yl)-1-propanone; 1-(1-Methylindol-3-yl)-3-(5-methylimidazol-4-yl)propan-1-one; 3-(5-Methylimidazol-4-yl)-1-(1-methylindol-3-yl)propan-1-one; 113140-33-3; Propanone, 3-(5-methyl-1H-imidazol-4-yl)-1-(1-methyl-1H-indol-3-yl)-
EINECS	Contact for details

Quality Control

Every batch of 3-(5-Methyl-1H-Imidazol-4-Yl)-1-(1-Methyl-1H-Indol-3-Yl)-1-Propanone is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment. We support development and commercial projects requiring compliance with ICH guidelines and can supply material suitable for use under cGMP conditions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.