Description

(R)-(4-Chlorophenyl)(Pyridin-2-Yl)Methanol CAS NO 112966-26-4 is a chiral alcohol compound featuring a pyridine and a chlorophenyl moiety, serving as a valuable intermediate in asymmetric synthesis. Its significance lies in its role as a key building block for the development of active pharmaceutical ingredients (APIs) and advanced materials, where stereochemical purity is critical. This product is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in the synthesis of chiral molecules.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides where specific stereochemistry enhances efficacy and reduces environmental impact.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis (e.g., hydrogenation, cross-coupling reactions).
• Material Science Research: Employed in the creation of chiral monomers for advanced polymers and liquid crystalline materials.
• Academic & Industrial R&D: A versatile building block for methodological development in organic and medicinal chemistry laboratories.

Basic Information

Product Name	(R)-(4-Chlorophenyl)(Pyridin-2-Yl)Methanol
CAS No.	112966-26-4
Molecular Formula	C12H10ClNO
Molecular Weight	219.67 g/mol
Synonyms	(R)-[4-Chlorophenyl](2-pyridinyl)methanol; (R)-α-(4-Chlorophenyl)-2-pyridinemethanol; (R)-2-Pyridyl(4-chlorophenyl)methanol; (R)-CPPM; (R)-4-Chlorophenyl(pyridin-2-yl)methanol; (R)-Enantiomer of 4-Chlorophenyl-2-pyridylmethanol; (R)-1-(4-Chlorophenyl)-1-(pyridin-2-yl)methanol
EINECS	Contact for details

Quality Control

Our (R)-(4-Chlorophenyl)(Pyridin-2-Yl)Methanol is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, NMR, and mass spectrometry for structural confirmation. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.