Description

1-(4'-Methyl)-Phenyl-1,2,3,4-Tetrahydro-Isoquinoline is a versatile heterocyclic organic compound belonging to the tetrahydroisoquinoline class, serving as a crucial synthetic intermediate and building block in advanced organic synthesis. Its value lies in its unique fused ring structure, which provides a rigid scaffold for constructing complex molecules with potential biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the development of central nervous system (CNS) agents, alkaloid analogs, and other pharmacologically active substances.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of novel bioactive compounds.
• Alkaloid Synthesis: Serves as a precursor in the synthesis of complex tetrahydroisoquinoline alkaloids and their derivatives.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new organic reactions and heterocyclic chemistry.
• Ligand & Catalyst Development: Potential use in creating chiral ligands or organocatalysts due to its nitrogen-containing structure.

Basic Information

Product Name	1-(4'-Methyl)-Phenyl-1,2,3,4-Tetrahydro-Isoquinoline
CAS No.	112891-31-3
Molecular Formula	C₁₆H₁₇N
Molecular Weight	223.31 g/mol
Synonyms	1-(4-Methylphenyl)-1,2,3,4-tetrahydroisoquinoline; 1-(p-Tolyl)-1,2,3,4-tetrahydroisoquinoline; 1-(4'-Methylphenyl)-1,2,3,4-tetrahydroisoquinoline; 4-Methyl-1,2,3,4-tetrahydroisoquinoline; 1-(4-Methylphenyl)-3,4-dihydroisoquinoline; Tetrahydroisoquinoline derivative; p-Tolyltetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our 1-(4'-Methyl)-Phenyl-1,2,3,4-Tetrahydro-Isoquinoline is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.