Description

(2-Cyclopropyl-2-Oxoethyl)Triphenyl-Phosphonium Bromide is a high-purity, specialized organophosphorus salt widely used as a key reagent in advanced organic synthesis. Its primary value lies in its role as a stabilized ylide precursor for Wittig and related olefination reactions, enabling the efficient construction of complex molecular frameworks. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for creating novel compounds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing cyclopropyl or olefinic motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific alkene geometries.
• Wittig Reaction Reagent: Serves as a specialized phosphonium ylide precursor for the formation of carbon-carbon double bonds with high stereoselectivity in fine chemical synthesis.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and other functional materials where precise olefin installation is required.
• Academic & Industrial R&D: A valuable tool for method development and the exploration of new synthetic pathways in organic chemistry laboratories.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule production under cGMP or research-grade conditions.

Basic Information

Product Name	(2-Cyclopropyl-2-Oxoethyl)Triphenyl-Phosphonium Bromide
CAS No.	112849-15-7
Molecular Formula	C23H22BrOP
Molecular Weight	425.30 g/mol
Synonyms	(2-Oxo-2-cyclopropylethyl)triphenylphosphonium bromide; 2-Cyclopropanecarbonylethyltriphenylphosphonium bromide; Triphenyl(2-cyclopropyl-2-oxoethyl)phosphonium bromide; Acetylcyclopropane triphenylphosphonium bromide; (Cyclopropylcarbonylmethyl)triphenylphosphonium bromide; Phosphonium, (2-cyclopropyl-2-oxoethyl)triphenyl-, bromide
EINECS	Contact for details

Quality Control

Every batch of (2-Cyclopropyl-2-Oxoethyl)Triphenyl-Phosphonium Bromide is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality commitment supports compliance in regulated environments, including those following ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect reactivity and stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.