Description

(R)-1-(4-Trifluoromethylphenyl)-1-Propanol CAS NO 112777-69-2 is a high-value chiral intermediate characterized by its trifluoromethylphenyl group and secondary alcohol functionality. This compound is critical for its role in imparting unique physicochemical properties, such as enhanced metabolic stability and lipophilicity, to final active molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of advanced, optically pure compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of chiral active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the chiral center and fluorine atoms contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and liquid crystals due to its aromatic and fluorinated structure.
• Reference Standard: Utilized as a high-purity analytical standard for method development and quality control in chiral separation techniques.

Basic Information

Product Name	(R)-1-(4-Trifluoromethylphenyl)-1-Propanol
CAS No.	112777-69-2
Molecular Formula	C10H11F3O
Molecular Weight	204.19 g/mol
Synonyms	(R)-1-[4-(Trifluoromethyl)phenyl]propan-1-ol; (R)-α-Ethyl-4-(trifluoromethyl)benzenemethanol; (R)-1-(4-Trifluoromethylphenyl)propyl alcohol; (R)-1-(p-Trifluoromethylphenyl)-1-propanol; (R)-4-Trifluoromethyl-α-ethylbenzyl alcohol; (R)-HPP-TFM; (R)-TFMPP
EINECS	Contact for details

Quality Control

Our (R)-1-(4-Trifluoromethylphenyl)-1-Propanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay by HPLC, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.