Description

(R)-(+)-1-(3'-Chlorophenyl)Propan-1-Ol CAS NO 112777-67-0 is a high-purity chiral alcohol intermediate, specifically the (R)-enantiomer, characterized by its 3-chlorophenyl substituent. This compound is of significant commercial value as a critical building block in the asymmetric synthesis of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure APIs, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the production of chiral herbicides, fungicides, and plant growth regulators where specific stereochemistry is required for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and auxiliaries used in asymmetric catalysis (e.g., hydrogenation, alkylation).
• Fine Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating libraries of chiral compounds.
• Flavor and Fragrance Industry: Potential intermediate for the synthesis of specific chiral aroma chemicals, though this application is more specialized.

Basic Information

Item	Details
Product Name	(R)-(+)-1-(3'-Chlorophenyl)Propan-1-Ol
CAS No.	112777-67-0
Molecular Formula	C9H11ClO
Molecular Weight	170.64 g/mol
Synonyms	(R)-1-(3-Chlorophenyl)-1-propanol; (R)-(+)-1-(3-Chlorophenyl)propan-1-ol; (R)-3-Chlorophenylpropyl alcohol; (R)-3'-Chloropropiophenone alcohol; (R)-m-Chlorophenylpropanol; (+)-(R)-1-(3-Chlorophenyl)propanol; (R)-CPPO; (R)-3-CPP
EINECS	Contact for details

Quality Control

Our production of (R)-(+)-1-(3'-Chlorophenyl)Propan-1-Ol adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure high enantiomeric excess (e.e.) and chemical purity. Certificates of Analysis (COA) detailing identity, assay, chiral purity, and impurity profiles are provided and available upon request, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (e.e.)	≥ 99.0%
Specific Rotation [α]	+XX° to +XX° (c=1 in solvent)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.