Description

[[(1A,3B,5E,7E)-9,10-Secocholesta-5,7,10(19)-Triene-1,3-Diyl]Bis(Oxy)]Bis[(1,1-Dimethylethyl)Dimethylsilane] CAS NO 112670-85-6 is a high-purity, protected intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a key synthetic precursor in the production of vitamin D analogs and other steroidal pharmaceuticals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing new therapeutic agents and conducting critical process chemistry.

Application

• Pharmaceutical Intermediate: A critical protected precursor in the multi-step synthesis of active vitamin D3 metabolites (e.g., calcitriol, tacalcitol) and their structural analogs.
• Steroid Chemistry Research: Used in academic and industrial R&D for exploring novel steroid derivatives with potential biological activity.
• Process Development: Serves as a standardized building block for scaling up and optimizing manufacturing routes for sterol-based active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Employed in the custom synthesis of complex, high-value organic molecules for specialized applications.
• Biochemical Tool Compound: May be utilized in studies investigating the vitamin D endocrine system and related metabolic pathways.

Basic Information

Product Name	[[(1A,3B,5E,7E)-9,10-Secocholesta-5,7,10(19)-Triene-1,3-Diyl]Bis(Oxy)]Bis[(1,1-Dimethylethyl)Dimethylsilane]
CAS No.	112670-85-6
Molecular Formula	C39H68O2Si2
Molecular Weight	625.1 g/mol
Synonyms	1,3-Bis(tert-butyldimethylsilyloxy)-9,10-secocholesta-5,7,10(19)-triene; (5E,7E)-1,3-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-9,10-secocholesta-5,7,10(19)-triene; 1α,3β-Bis-O-(tert-butyldimethylsilyl)-9,10-secocholesta-5,7,10(19)-triene; Vitamin D3 1,3-Bis-TBDMS Ether; TBS-protected Vitamin D3 intermediate; 1,3-di-TBDMS-cholestatrienol; 1,3-Bis-O-TBDMS-9,10-secocholestatrienol
EINECS	Contact for details

Quality Control

Our [[(1A,3B,5E,7E)-9,10-Secocholesta-5,7,10(19)-Triene-1,3-Diyl]Bis(Oxy)]Bis[(1,1-Dimethylethyl)Dimethylsilane] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.