Description

Trimethylsilyl (2-Methoxyphenoxy)Acetate is a specialized organosilicon reagent used as a key synthetic intermediate in advanced organic chemistry. Its primary value lies in its role as a protected or activated form of (2-methoxyphenoxy)acetic acid, facilitating efficient coupling reactions and the synthesis of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and fine chemicals where precise molecular construction is critical.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Peptide Mimetics & Conjugation: Serves as a reagent for introducing the (2-methoxyphenoxy)acetyl moiety into peptides or other biomolecules.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed reactions.
• Polymer & Material Science: Acts as a monomer or modifier in the synthesis of functionalized polymers and advanced materials.
• Protecting Group Strategy: The trimethylsilyl (TMS) group can act as a temporary protecting group for carboxylic acids in multi-step syntheses.

Basic Information

Product Name	Trimethylsilyl (2-Methoxyphenoxy)Acetate
CAS No.	112309-83-8
Molecular Formula	C₁₄H₂₂O₄Si
Molecular Weight	282.41 g/mol
Synonyms	Acetic acid, 2-(2-methoxyphenoxy)-, trimethylsilyl ester; (2-Methoxyphenoxy)acetic acid trimethylsilyl ester; Trimethylsilyl 2-(2-methoxyphenoxy)acetate; TMS (2-methoxyphenoxy)acetate; 2-(2-Methoxyphenoxy)acetic acid TMS ester; [Trimethylsilyloxycarbonylmethyl](2-methoxyphenoxy)methane
EINECS	Contact for details

Quality Control

Our Trimethylsilyl (2-Methoxyphenoxy)Acetate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles. We are committed to meeting the stringent requirements of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.