Description

(L-Leucinethiol)2 2 Hcl is a specialized biochemical building block, specifically a dimeric derivative of L-leucine modified with a thiol group. This compound is valued for its role in advanced peptide synthesis and as a precursor for creating complex molecular architectures, particularly in pharmaceutical research and development. It is essential for scientists and manufacturers in the fields of medicinal chemistry, proteomics, and the development of novel therapeutic agents and biochemical probes.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Bioconjugation & Protein Engineering: Used for site-specific labeling, cross-linking, or functionalization of proteins and antibodies due to its reactive thiol group.
• Chemical Biology Research: Acts as a key reagent in the development of enzyme inhibitors, activity-based probes, and other research tools.
• Material Science: Potential applications in creating functionalized surfaces or polymers with specific biomimetic properties.
• Peptide Library Synthesis: Employed in combinatorial chemistry for generating diverse peptide libraries for screening purposes.

Basic Information

Product Name	(L-Leucinethiol)2 2 Hcl
CAS No.	112157-33-2
Molecular Formula	C12H26N2O2S2 • 2HCl
Molecular Weight	375.39 g/mol (free base: 286.48 g/mol)
Synonyms	Bis(L-leucinethiol) dihydrochloride; L-Leucine, thio-, dimer, dihydrochloride; (L-LeucineSH)2•2HCl; N,N'-Bis(2-amino-4-methyl-1-oxopentyl)-L-cystamine dihydrochloride; 1,1'-[Dithiobis(2,1-ethanediylimino(1-oxo-4-methyl-2,1-pentanediyl))]bis-L-leucine dihydrochloride
EINECS	Contact for details

Quality Control

Our (L-Leucinethiol)2 2 Hcl is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and moisture. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.