Description

Alpha,α-Diphenyl-L-Prolinol is a high-value, non-natural amino alcohol derivative characterized by its chiral diphenylprolinol structure. This compound matters as a versatile and highly effective organocatalyst, enabling asymmetric synthesis with excellent enantioselectivity and yield. It is critically needed by research chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex chiral molecules.

Application

• Asymmetric Organocatalysis: A premier catalyst for a wide range of enantioselective reactions, including aldol, Michael, Mannich, and Diels-Alder reactions.
• Pharmaceutical Intermediate Synthesis: Key building block and chiral auxiliary in the synthesis of active pharmaceutical ingredients (APIs) requiring high optical purity.
• Agrochemical Research: Used in the development of chiral pesticides and herbicides where specific stereochemistry is crucial for activity.
• Academic & Industrial R&D: Essential reagent for methodological development in organic chemistry and scale-up process optimization.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that demand enantiomerically pure compounds.

Basic Information

Product Name	Alpha,α-Diphenyl-L-Prolinol
CAS No.	112068-08-3
Molecular Formula	C₁₇H₁₉NO
Molecular Weight	253.34 g/mol
Synonyms	(S)-(-)-2-(Diphenylhydroxymethyl)pyrrolidine; (S)-(-)-α,α-Diphenyl-2-pyrrolidinemethanol; L-Prolinol, α,α-diphenyl-; Diphenylprolinol; (S)-α,α-Diphenylprolinol; Jørgensen-Hayashi Catalyst; Organocatalyst; (S)-2-(Diphenylhydroxymethyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our Alpha,α-Diphenyl-L-Prolinol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for catalytic and synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and catalytic activity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.