Description

Fluoromethyltriphenylphosphonium Bromide is a high-value organophosphorus salt widely used as a key reagent in organic synthesis. Its primary value lies in its role as a fluoromethylenation agent, enabling the efficient introduction of fluorinated methylene groups into complex molecular frameworks. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise fluorination chemistry for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate Synthesis: A crucial reagent for constructing fluorinated analogs of drug candidates, enhancing metabolic stability and bioavailability.
• Agrochemical Development: Used in the synthesis of fluorinated pesticides and herbicides, where the fluorine atom can improve efficacy and environmental profile.
• Wittig Reaction Reagent: Serves as a specialized ylide precursor for the Wittig olefination reaction to generate fluorinated alkenes.
• Material Science Research: Employed in the creation of fluorinated polymers and liquid crystals with unique electronic and surface properties.
• Radiochemistry & Tracer Synthesis: Useful in the preparation of compounds for Positron Emission Tomography (PET) imaging agents containing fluorine-18.
• Academic & Process Chemistry: A valuable building block in methodological research and scale-up process development for fluoroorganic chemistry.

Basic Information

Product Name	Fluoromethyltriphenylphosphonium Bromide
CAS No.	111902-74-0
Molecular Formula	C20H19BrFP+
Molecular Weight	380.24 g/mol
Synonyms	(Fluoromethyl)triphenylphosphonium Bromide; Fluoromethyl Triphenylphosphonium Bromide; Triphenyl(fluoromethyl)phosphonium Bromide; (Fluoromethyl)triphenyl-λ5-phosphanuidyl Bromide; FCH2PPh3Br; Fluoromethylene Triphenylphosphorane Hydrobromide; Fluoromethyltriphenylphosphonium Bromide Salt
EINECS	Contact for details

Quality Control

Our Fluoromethyltriphenylphosphonium Bromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.