Description

(R)-3,3'-Bis(Triphenylsilyl)-1,1'-Bi-2-naphthol is a chiral, axially hindered binaphthol derivative functionalized with bulky triphenylsilyl groups at the 3,3' positions. This compound matters as a highly effective and selective chiral ligand or catalyst precursor in asymmetric synthesis, where its steric bulk and defined chirality are critical for inducing high enantioselectivity. It is primarily needed by research and development chemists in the pharmaceutical and fine chemical industries for applications such as asymmetric hydrogenation, C-C bond formation, and other enantioselective transformations.

Application

• Asymmetric Catalysis: As a chiral ligand for transition metals (e.g., Rh, Ru, Pd) in enantioselective hydrogenation, coupling, and addition reactions.
• Chiral Auxiliary: Employed in the synthesis of enantiomerically pure intermediates for active pharmaceutical ingredients (APIs).
• Material Science: Potential precursor for chiral polymers or as a dopant in liquid crystal displays (LCDs) to induce helical structures.
• Organic Synthesis: Used in the preparation of other complex chiral ligands or as a resolving agent.
• Academic & Industrial R&D: A valuable tool for methodology development in stereoselective synthesis.

Basic Information

Product Name	(R)-3,3'-Bis(Triphenylsilyl)-1,1'-Bi-2-naphthol
CAS No.	111822-69-6
Molecular Formula	C62H44O2Si2
Molecular Weight	901.19 g/mol
Synonyms	(R)-3,3'-Bis(triphenylsilyl)-2,2'-dihydroxy-1,1'-binaphthyl; (R)-3,3'-Di(triphenylsilyl)-1,1'-bi-2-naphthol; (R)-3,3'-Bis(triphenylsilyl)-1,1'-binaphthyl-2,2'-diol; (R)-BINOL-3,3'-bis(triphenylsilyl) ether; (R)-DTB-SEGPHOS precursor; Chiral binaphthol silyl ether; (R)-3,3'-TIPS-BINOL (common abbreviation)
EINECS	Contact for details

Quality Control

Our (R)-3,3'-Bis(Triphenylsilyl)-1,1'-Bi-2-naphthol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure compliance with research and process development standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.