Description

2-(5-Bromothiophen-2-Yl)Piperazine is a high-value brominated heterocyclic building block, a piperazine derivative functionalized with a bromothiophene moiety. This compound is essential for medicinal chemistry and pharmaceutical research, serving as a critical intermediate in the synthesis of novel bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets and kinase inhibitors.
• Agrochemical Research: Building block for developing new active ingredients in crop protection and pest management products.
• Material Science: Used in the development of organic semiconductors, conductive polymers, and advanced organic electronic materials.
• Chemical Biology: Serves as a versatile scaffold for creating molecular probes and tool compounds for biological target validation.
• Custom Synthesis: Employed in contract research and manufacturing (CRO/CMO) for bespoke chemical synthesis and library production.
• Academic Research: Fundamental research reagent in universities and institutes for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-(5-Bromothiophen-2-Yl)Piperazine
CAS No.	111760-29-3
Molecular Formula	C8H11BrN2S
Molecular Weight	247.16 g/mol
Synonyms	5-Bromo-2-(piperazin-1-yl)thiophene; 1-(5-Bromothiophen-2-yl)piperazine; 2-(5-Bromo-2-thienyl)piperazine; 5-Bromo-2-piperazin-1-ylthiophene; 111760-29-3; 2-Piperazinyl-5-bromothiophene
EINECS	Contact for details

Quality Control

Our 2-(5-Bromothiophen-2-Yl)Piperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere or in a controlled environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.