Description

2-(Chloroacetyl)-6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline is a key synthetic intermediate in organic chemistry, specifically a functionalized tetrahydroisoquinoline derivative. This compound matters for its role as a versatile building block in the synthesis of complex pharmaceutical molecules and bioactive alkaloids. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various tetrahydroisoquinoline-based active pharmaceutical ingredients (APIs) and drug candidates.
• Alkaloid Synthesis: Used as a building block for constructing complex natural product analogs and bioactive alkaloids with potential therapeutic applications.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities in drug discovery programs.
• Process Chemistry: Employed in route scouting and scale-up processes for the commercial manufacturing of specialty chemicals.
• Agrochemical Research: Potential intermediate in the development of novel pesticides or herbicides due to its heterocyclic structure.
• Chemical Biology Probes: Can be utilized to create molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	2-(Chloroacetyl)-6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline
CAS No.	111631-72-2
Molecular Formula	C₁₃H₁₆ClNO₃
Molecular Weight	269.72 g/mol
Synonyms	6,7-Dimethoxy-2-(chloroacetyl)-1,2,3,4-tetrahydroisoquinoline; 2-Chloro-1-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethanone; 1-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-2-chloroethan-1-one; 2-(Chloroacetyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; 6,7-Dimethoxy-2-(2-chloroacetyl)-1,2,3,4-tetrahydroisoquinoline; 2-(2-Chloroacetyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our 2-(Chloroacetyl)-6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed specifications, including assay by HPLC, impurity profiles, and physical characterization. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.