Description

(E)-Ethyl 3-(Thiazol-4-Yl)Acrylate is a high-purity, versatile chemical building block featuring a conjugated acrylate ester linked to a thiazole heterocycle. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is essential for chemists and manufacturers developing active ingredients, functional materials, and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial synthon for the development of active pharmaceutical ingredients (APIs), especially in antiviral, anticancer, and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging the bioactivity of the thiazole moiety.
• Material Science Research: Serves as a monomer or precursor for functional polymers, liquid crystals, and organic electronic materials due to its conjugated system.
• Chemical Biology & Proteomics: Employed as a building block for synthesizing probes, tags, and linkers used in bioconjugation and target identification studies.
• Organic Synthesis & Catalysis: A valuable substrate in cross-coupling reactions, cycloadditions, and other catalytic processes to construct complex heterocyclic frameworks.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments where the thiazole-acrylate structure imparts specific color and stability properties.

Basic Information

Product Name	(E)-Ethyl 3-(Thiazol-4-Yl)Acrylate
CAS No.	111601-00-4
Molecular Formula	C8H9NO2S
Molecular Weight	183.23 g/mol
Synonyms	Ethyl (E)-3-(4-Thiazolyl)acrylate; Ethyl (E)-3-(Thiazol-4-yl)propenoate; trans-Ethyl 3-(4-Thiazolyl)acrylate; 4-Thiazoleacrylic Acid Ethyl Ester; (E)-Ethyl 3-(1,3-Thiazol-4-yl)acrylate; Ethyl 3-(4-Thiazolyl)-2-propenoate; 2-Propenoic acid, 3-(4-thiazolyl)-, ethyl ester, (E)-
EINECS	Contact for details

Quality Control

Our (E)-Ethyl 3-(Thiazol-4-Yl)Acrylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.