Description

n-(2'-Mercaptoethyl)Lactamine CAS NO 111435-50-8 is a specialized organosulfur compound featuring both a lactam ring and a terminal thiol (mercapto) functional group. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily sought by R&D chemists and process development scientists in the life sciences, agrochemical, and advanced material sectors for constructing novel drug candidates, ligands, and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting neurological or oncological pathways.
• Bioconjugation Reagent: Utilized for coupling peptides, proteins, or other biomolecules via its reactive thiol group, enabling drug-antibody conjugates or diagnostic probes.
• Polymer Modification: Serves as a functional monomer or cross-linking agent to introduce thiol groups into polymer backbones for creating responsive or self-healing materials.
• Catalyst Ligand Synthesis: Used to prepare chelating ligands for metal catalysts in asymmetric synthesis and homogeneous catalysis.
• Agrochemical Research: Intermediate in the development of new herbicides, fungicides, or plant growth regulators with enhanced activity.
• Cosmetic Ingredient Synthesis: Precursor for compounds used in advanced skincare formulations, such as antioxidants or skin-conditioning agents.

Basic Information

Product Name	n-(2'-Mercaptoethyl)Lactamine
CAS No.	111435-50-8
Molecular Formula	C8H15NOS
Molecular Weight	173.28 g/mol
Synonyms	2-(2-Mercaptoethyl)-2-pyrrolidinone; 1-(2-Mercaptoethyl)-2-pyrrolidinone; N-(2-Mercaptoethyl)-2-pyrrolidinone; 2-Pyrrolidinone, 1-(2-mercaptoethyl)-; Lactamine, N-(2'-mercaptoethyl)-; AEBSF Lactam Derivative; Thiol-functionalized lactam
EINECS	Contact for details

Quality Control

Our n-(2'-Mercaptoethyl)Lactamine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and Karl Fischer titration for water content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production standards. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. The material is easily oxidized; prolonged exposure to air or elevated temperatures should be avoided. Keep the container in a cool, dry, and well-ventilated place, away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.