Description

2-Amino-1-Phenylethanol is a versatile chiral amino alcohol building block of significant importance in fine chemical synthesis. Its bifunctional structure, featuring both a primary amine and a secondary alcohol, makes it a critical intermediate for constructing complex molecules with high stereochemical control. This compound is essential for research and production in the pharmaceutical and agrochemical industries, where it serves as a precursor to active pharmaceutical ingredients (APIs), chiral ligands, and catalysts.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of adrenergic drugs, β-blockers (e.g., analogs of propranolol), and other bioactive molecules.
• Asymmetric Catalysis: Used in the preparation of chiral ligands and organocatalysts for enantioselective synthesis.
• Agrochemical Synthesis: Building block for developing chiral herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Intermediate in the manufacture of dyes, flavors, and fragrances requiring specific stereochemistry.
• Research & Development: Valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and drug discovery.
• Resolution Agent: Employed as a resolving agent for the separation of racemic mixtures of acids.

Basic Information

Product Name	2-Amino-1-Phenylethanol
CAS No.	111025-00-4
Molecular Formula	C8H11NO
Molecular Weight	137.18 g/mol
Synonyms	2-Amino-1-phenylethanol; (RS)-2-Amino-1-phenylethanol; (±)-2-Amino-1-phenylethanol; DL-2-Amino-1-phenylethanol; 1-Phenyl-2-aminoethanol; 2-Amino-2-phenylethanol; α-(Aminomethyl)benzyl alcohol; Norphenylephrine; NSC 403697; β-Amino-α-hydroxybenzeneethane
EINECS	Contact for details

Quality Control

Our 2-Amino-1-Phenylethanol is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications including assay, chiral purity (enantiomeric excess), and impurity profiles. Quality standards can be tailored to meet specific customer requirements, including compliance with cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (ee)	Contact for details (Racemic or Enantiopure grades available)
Melting Point	Approx. 85 - 90 °C
Loss on Drying	≤ 1.0 %
Residue on Ignition	≤ 0.1 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.