Description

Phosphonic Acid, (4-Oxo-2-Butenyl)-, Diethyl Ester, (E)- is a specialized organophosphorus compound that serves as a versatile synthetic intermediate. Its molecular structure, featuring both a phosphonate ester and an α,β-unsaturated ketone (enone) moiety, makes it a valuable building block for the synthesis of complex molecules. This chemical is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting bone diseases or requiring phosphonate-based bioisosteres.
• Agrochemical Synthesis: Building block for creating advanced herbicides, plant growth regulators, and fungicides with specific mode-of-action profiles.
• Ligand and Catalyst Development: Used to prepare chelating ligands for metal catalysis and coordination chemistry applications.
• Material Science Research: Intermediate for synthesizing functional polymers, flame retardants, or surface-modifying agents.
• Chemical Biology Probes: Serves as a scaffold for developing activity-based probes or enzyme inhibitors targeting metabolic pathways.

Basic Information

Item	Details
Product Name	Phosphonic Acid, (4-Oxo-2-Butenyl)-, Diethyl Ester, (E)-
CAS No.	110905-37-8
Molecular Formula	C8H15O4P
Molecular Weight	206.18 g/mol
Synonyms	(E)-Diethyl (4-oxobut-2-en-1-yl)phosphonate; (E)-1-Diethoxyphosphoryl-3-buten-2-one; trans-4-Oxo-2-butenylphosphonic Acid Diethyl Ester; Diethyl (E)-(4-Oxo-2-butenyl)phosphonate; (E)-4-Oxo-2-butenylphosphonic Acid Diethyl Ester; (E)-3-Buten-2-one, 1-(diethoxyphosphinyl)-; (E)-1-(Diethoxyphosphoryl)but-3-en-2-one
EINECS	Contact for details

Quality Control

Our production of Phosphonic Acid, (4-Oxo-2-Butenyl)-, Diethyl Ester, (E)- adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic workflows. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and GC to confirm identity, isomeric purity (E-configuration), and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure containers are sealed properly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (E-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.