Description

5-Amino-1-[5-(Fluoromethyl)Phenyl]-1H-Pyrazole-4-Carboxylic Acid Ethyl Ester is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its unique molecular architecture, featuring both a reactive amino group and a fluoromethyl-substituted aromatic ring, making it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, particularly in therapeutic areas requiring fluorinated compounds for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a building block for developing advanced pesticides, herbicides, and fungicides, where the fluorine atom can improve biological activity and environmental persistence.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its conjugated pyrazole core and functional groups.
• Chemical Biology & Proteomics: Employed as a scaffold or labeling agent in the design of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	5-Amino-1-[5-(Fluoromethyl)Phenyl]-1H-Pyrazole-4-Carboxylic Acid Ethyl Ester
CAS No.	110821-29-9
Molecular Formula	C14H16FN3O2
Molecular Weight	277.30 g/mol
Synonyms	Ethyl 5-Amino-1-[5-(fluoromethyl)phenyl]-1H-pyrazole-4-carboxylate; 5-Amino-1-(5-fluoromethylphenyl)-1H-pyrazole-4-carboxylic acid ethyl ester; 1H-Pyrazole-4-carboxylic acid, 5-amino-1-[5-(fluoromethyl)phenyl]-, ethyl ester; 5-Amino-1-(5-fluorobenzyl)-1H-pyrazole-4-carboxylic acid ethyl ester (common name); 110821-29-9; 5-Amino-1-(5-fluoromethylphenyl)pyrazole-4-ethyl carboxylate
EINECS	Contact for details

Quality Control

Our 5-Amino-1-[5-(Fluoromethyl)Phenyl]-1H-Pyrazole-4-Carboxylic Acid Ethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding R&D and scale-up processes. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with every batch to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to prevent decomposition. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.