Description

Dmt-2'o-Methyl-Ru Phosphoramidite is a high-purity, specialty phosphoramidite monomer used in the automated solid-phase synthesis of oligonucleotides. This compound is critical for introducing site-specific modifications into DNA or RNA strands, enabling advanced research and therapeutic development. It is an essential building block for biotechnology, pharmaceutical R&D, and diagnostic companies working on antisense oligonucleotides, siRNA, and other nucleic acid-based technologies.

Application

• Oligonucleotide Synthesis: As a key monomer for the automated synthesis of modified DNA and RNA strands.
• Therapeutic Nucleic Acid Development: For creating antisense oligonucleotides (ASOs), small interfering RNA (siRNA), and aptamers with enhanced stability and specificity.
• Diagnostic Probe Manufacturing: Used in the production of labeled probes for genetic testing, fluorescence in situ hybridization (FISH), and microarray technologies.
• Basic Research: Enables academic and industrial research into nucleic acid structure, function, and protein interactions.
• Next-Generation Sequencing (NGS): Can be utilized in the preparation of specialized primers and adapters for advanced sequencing platforms.

Basic Information

Product Name	Dmt-2'o-Methyl-Ru Phosphoramidite
CAS No.	110764-79-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyluridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 2'-O-Methyl-5'-O-DMT-uridine-3'-CE-phosphoramidite; 2'-O-Me-U Phosphoramidite; DMT-2'-O-Methyl-U Phosphoramidite; 2'-O-Methyluridine Phosphoramidite; 2'-O-Me-Ur Phosphoramidite; RNA Phosphoramidite Monomer
EINECS	Contact for details

Quality Control

Every batch of Dmt-2'o-Methyl-Ru Phosphoramidite is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure it meets the stringent requirements of oligonucleotide synthesis. Our products are supported by a detailed Certificate of Analysis (COA) that includes purity assessment by HPLC, identity confirmation, and moisture content. We adhere to industry best practices to guarantee reproducible performance and supply chain reliability for our global customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a recommended temperature of -20°C or below under an inert atmosphere (argon or nitrogen) due to its moisture-sensitive and light-sensitive nature. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid or foam
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.