Description

(R)-6,7-Dimethoxy-1-Methyl-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is a chiral tetrahydroisoquinoline derivative of significant synthetic and pharmacological interest. This compound serves as a crucial chiral building block and intermediate in the research and development of active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and asymmetric synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex alkaloids and potential therapeutic agents.
• Medicinal Chemistry Research: Used as a scaffold or precursor for developing novel compounds targeting neurological and cardiovascular receptors.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective chemical transformations.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Biochemical Research: Used in studies investigating enzyme inhibition and receptor-ligand interactions.
• Process Chemistry Development: A critical intermediate for scaling up the production of chiral drug candidates.

Basic Information

Product Name	(R)-6,7-Dimethoxy-1-Methyl-1,2,3,4-Tetrahydroisoquinoline Hydrochloride
CAS No.	110691-65-1
Molecular Formula	C₁₂H₁₈ClNO₂
Molecular Weight	243.73 g/mol
Synonyms	(R)-1-Methyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride; (R)-6,7-Dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline HCl; (R)-1-Methyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline HCl; (R)-6,7-Dimethoxy-1-methyl-THIQ hydrochloride; (R)-1-Methyl-6,7-dimethoxy-THIQ hydrochloride; (R)-6,7-Dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinolinium chloride; (R)-1-Methyl-6,7-dimethoxy-3,4-dihydroisoquinoline hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-6,7-Dimethoxy-1-Methyl-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.