Description

1-Acetyl-2,3-Dihydro-1H-Indole-2-Carboxylic Acid is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its fused indoline-acetic acid structure, which serves as a critical scaffold for constructing complex molecules with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its heterocyclic core.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor or building block in the synthesis of specialized electron-transport or host materials.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands or metal-organic complexes for asymmetric catalysis.
• Academic and Contract Research: A valuable reagent for methodological studies and the synthesis of complex natural product analogs in university and CRO laboratories.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals for various high-value industrial applications.

Basic Information

Item	Detail
Product Name	1-Acetyl-2,3-Dihydro-1H-Indole-2-Carboxylic Acid
CAS No.	110659-07-9
Molecular Formula	C11H11NO3
Molecular Weight	205.21 g/mol
Synonyms	2-Carboxy-1-acetylindoline; 1-Acetylindoline-2-carboxylic Acid; 2,3-Dihydro-1-acetyl-1H-indole-2-carboxylic Acid; 1H-Indole-2-carboxylic acid, 2,3-dihydro-1-acetyl-; 1-Acetyl-2,3-dihydroindole-2-carboxylic acid; 1-Acetylindoline-2-carboxylic acid; 2-(Acetylamino)benzenepropanoic acid (tautomeric form)
EINECS	Contact for details

Quality Control

Our 1-Acetyl-2,3-Dihydro-1H-Indole-2-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.