Description

3-Bromo-4-Methoxythiophene is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactive bromine substituent and electron-donating methoxy group, which facilitate selective cross-coupling reactions and functional group transformations. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, enabling the development of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting central nervous system and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the thiophene scaffold for enhanced bioactivity.
• Organic Electronic Materials: Serves as a monomer or building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), field-effect transistors (OFETs), and solar cells.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis, facilitating challenging chemical transformations.
• Chemical Research & Development: A valuable reagent for medicinal chemistry, process chemistry, and material science R&D for exploring new synthetic pathways.
• Functional Dyes and Pigments: Intermediate in the production of specialized dyes and pigments where the thiophene core contributes to color and stability properties.

Basic Information

Product Name	3-Bromo-4-Methoxythiophene
CAS No.	110545-69-2
Molecular Formula	C5H5BrOS
Molecular Weight	193.06 g/mol
Synonyms	4-Methoxy-3-bromothiophene; 3-Bromo-4-methoxythiophene; Thiophene, 3-bromo-4-methoxy-; 3-Brom-4-methoxythiophen; 3-Bromo-4-methyloxythiophene
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Methoxythiophene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and residual solvent analysis, to ensure high chemical purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.