Description

Methyl 4-Bromo-3-Methoxythiophene-2-Carboxylate is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its reactive bromine and ester functional groups, which allow for precise molecular construction and diversification. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the thiophene scaffold for bioactivity.
• Material Science Research: Serves as a monomer or building block for developing conjugated polymers and organic electronic materials due to the thiophene core.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Negishi couplings for carbon-carbon bond formation.
• Functional Group Transformation: The methyl ester group can be hydrolyzed to the corresponding acid or reduced to the alcohol, enabling further synthetic elaboration.
• Ligand and Catalyst Development: Utilized in the creation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Methyl 4-Bromo-3-Methoxythiophene-2-Carboxylate
CAS No.	110545-67-0
Molecular Formula	C7H7BrO3S
Molecular Weight	251.10 g/mol
Synonyms	4-Bromo-3-methoxy-2-thiophenecarboxylic acid methyl ester; Methyl 4-bromo-3-methoxy-2-thiophenecarboxylate; 2-Thiophenecarboxylic acid, 4-bromo-3-methoxy-, methyl ester; 4-Bromo-3-methoxythiophene-2-carboxylic acid methyl ester; MBMT; Methyl 4-bromo-3-methoxythiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Every batch of Methyl 4-Bromo-3-Methoxythiophene-2-Carboxylate is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and scale-up. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot and supplied with every order.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.