Description

n-Acetyl-G-Carbethoxy Homotryptophan, Ethyl Ester is a specialized, high-purity synthetic amino acid derivative designed for advanced research and pharmaceutical development. This compound serves as a critical chiral building block and intermediate in the synthesis of complex peptides and bioactive molecules. It is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking reliable, high-quality raw materials for API synthesis and novel drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic peptides and small molecule drugs.
• Peptide Synthesis: Used as a protected tryptophan analog in solid-phase and solution-phase peptide synthesis to introduce specific structural motifs.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and as a building block for creating focused compound libraries.
• Bioconjugation: Potential use in the development of antibody-drug conjugates (ADCs) and other targeted delivery systems due to its functionalizable groups.
• Process Chemistry: Serves as an intermediate in the scalable manufacturing of active pharmaceutical ingredients (APIs) requiring this specific molecular framework.
• Biochemical Research: Used in enzymatic studies and as a substrate analog to probe biological pathways and mechanisms.

Basic Information

Product Name	n-Acetyl-G-Carbethoxy Homotryptophan, Ethyl Ester
CAS No.	110504-56-8
Molecular Formula	C19H24N2O5
Molecular Weight	360.41 g/mol
Synonyms	N-[(Ethoxycarbonyl)acetyl]-L-tryptophan ethyl ester; N-Acetyl-α-carbethoxy-DL-homotryptophan ethyl ester; Ethyl N-acetyl-α-ethoxycarbonylhomotryptophanate; Ac-Gly(COOEt)-Trp-OEt; (2S)-2-Acetamido-3-[1H-indol-3-yl]methyl]-4-ethoxy-4-oxobutanoic acid ethyl ester; N-Acetyl-α-ethoxycarbonylhomotryptophan ethyl ester; L-Tryptophan, N-[(ethoxycarbonyl)acetyl]-, ethyl ester
EINECS	Contact for details

Quality Control

Our n-Acetyl-G-Carbethoxy Homotryptophan, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation by IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.