Description

n-Acetyl-D,L-Homotryptophan, Ethyl Ester is a chemically modified derivative of the amino acid tryptophan, serving as a key chiral building block and intermediate in advanced organic synthesis. Its value lies in providing a protected and functionalized scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel therapeutics, peptide mimetics, and other bioactive compounds requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting neurological and psychiatric disorders.
• Peptidomimetic Research: Used to create non-natural amino acid analogs for developing stable peptide-based therapeutics and probes.
• Chemical Biology Tool: Employed in the study of enzyme mechanisms and protein-protein interactions where a modified tryptophan residue is required.
• Asymmetric Synthesis: Acts as a chiral starting material or auxiliary for the construction of stereochemically complex molecules in fine chemical production.
• Academic & R&D: Serves as a standard or reagent in university and corporate research laboratories exploring new synthetic methodologies.

Basic Information

Product Name	n-Acetyl-D,L-Homotryptophan, Ethyl Ester
CAS No.	110504-55-7
Molecular Formula	C₁₇H₂₀N₂O₃
Molecular Weight	300.35 g/mol
Synonyms	Ethyl N-Acetyl-DL-homotryptophanate; DL-2-Acetamido-4-(3-indolyl)butyric Acid Ethyl Ester; N-Acetyl-DL-homotryptophan Ethyl Ester; Ac-DL-Hotrp-OEt; (±)-N-Acetylhomotryptophan Ethyl Ester; Ethyl (±)-2-acetamido-4-(1H-indol-3-yl)butanoate; 2-(Acetylamino)-4-(1H-indol-3-yl)butanoic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our n-Acetyl-D,L-Homotryptophan, Ethyl Ester is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. We provide comprehensive analytical data including HPLC purity, chiral purity, and spectroscopic confirmation (NMR, IR, MS). A Certificate of Analysis (COA) detailing all specifications is available with every shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	DL-Mixture (Racemic)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.