Description

1-(8-Chloro-5-Isoquinolinesulfonyl)Piperazine, Dihydrochloride is a high-purity, synthetic organic compound primarily utilized as a key intermediate in advanced pharmaceutical research and development. This compound is valued for its role in the synthesis of complex molecules, particularly those targeting specific enzymatic pathways. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality building blocks for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitor research.
• Biochemical Research: Used as a tool compound or precursor in enzymatic studies and proteomics research to investigate cellular signaling pathways.
• Chemical Synthesis: Serves as a versatile sulfonamide-containing scaffold for constructing complex heterocyclic compounds in medicinal chemistry.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Preclinical Development: Integral to the discovery phase for creating candidate molecules with potential therapeutic applications.

Basic Information

Product Name	1-(8-Chloro-5-Isoquinolinesulfonyl)Piperazine, Dihydrochloride
CAS No.	110408-12-3
Molecular Formula	C13H15Cl3N4O2S
Molecular Weight	397.70 g/mol
Synonyms	8-Chloro-5-(piperazin-1-ylsulfonyl)isoquinoline dihydrochloride; 1-[(8-Chloro-5-isoquinolinyl)sulfonyl]piperazine dihydrochloride; 110408-12-3; 8-Chloro-5-piperazin-1-ylsulfonyl-isoquinoline dihydrochloride; 1-(8-Chloro-5-isoquinolinesulfonyl)piperazine hydrochloride (1:2); Piperazine, 1-[(8-chloro-5-isoquinolinyl)sulfonyl]-, dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(8-Chloro-5-Isoquinolinesulfonyl)Piperazine, Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting compliance with cGMP and research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.