Description

5-Methoxy-2-[(3,5-Dimethyl-2-Pyridinyl)-Methylsulfinyl]-Benzimidazole is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for ensuring the quality and efficacy of final active pharmaceutical ingredients (APIs) in specific therapeutic areas. It is primarily required by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development and production of specialized drug candidates.

Application

• Key Intermediate in Proton Pump Inhibitor (PPI) Synthesis: Serves as a crucial building block in the production pathway for certain benzimidazole-based anti-ulcer medications.
• Pharmaceutical Research & Development (R&D): Used by medicinal chemists for structure-activity relationship (SAR) studies and the development of new therapeutic agents targeting gastric acid secretion.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in controlled synthesis processes for the commercial-scale production of specific finished APIs.
• Reference Standard: Supplied as a high-purity compound for analytical method development, validation, and quality control testing in regulatory submissions.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis for creating novel, complex molecules with potential biological activity.

Basic Information

Product Name	5-Methoxy-2-[(3,5-Dimethyl-2-Pyridinyl)-Methylsulfinyl]-Benzimidazole
CAS No.	110374-16-8
Molecular Formula	C₁₆H₁₇N₃O₂S
Molecular Weight	315.39 g/mol
Synonyms	5-Methoxy-2-[(3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole; 2-[[(3,5-Dimethyl-2-pyridinyl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole; CAS 110374-16-8; Ilaprazole Intermediate; IY-81149 Intermediate; (3,5-Dimethyl-2-pyridyl)methylsulfinyl-5-methoxybenzimidazole
EINECS	Contact for details

Quality Control

Our production of 5-Methoxy-2-[(3,5-Dimethyl-2-Pyridinyl)-Methylsulfinyl]-Benzimidazole adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.