Description

Adenine-2-D1 is a deuterium-labeled derivative of the fundamental nucleobase adenine, specifically deuterated at the 2-position. This stable isotope-labeled compound is essential for advanced analytical and research applications where precise molecular tracking is required. It is primarily utilized by researchers and manufacturers in the fields of pharmaceutical development, metabolic studies, and analytical chemistry.

Application

• Internal standard for the quantitative analysis of adenine and related metabolites via LC-MS (Liquid Chromatography-Mass Spectrometry) and GC-MS.
• Tracer compound in drug metabolism and pharmacokinetics (DMPK) studies to investigate absorption, distribution, metabolism, and excretion pathways.
• Key starting material or intermediate in the synthesis of deuterium-labeled nucleosides, nucleotides, and oligonucleotides for research.
• Use in NMR (Nuclear Magnetic Resonance) spectroscopy as a probe for studying molecular structure and dynamics.
• Biochemical research involving isotope dilution mass spectrometry to achieve high-precision quantification in complex biological matrices.
• Development of diagnostic assays and reference materials requiring stable isotope-labeled biomarkers.

Basic Information

Product Name	Adenine-2-D1
CAS No.	109923-52-6
Molecular Formula	C5H4DN5
Molecular Weight	136.13 g/mol
Synonyms	2-Deuterioadenine; Adenine-2-d; [2-2H]Adenine; 6-Aminopurine-2-d; 9H-Purin-6-amine-2-d1; 1H-Purin-6-amine-2-d1; Deuterated Adenine (2-D); Vitamin B4-d1 (labeled)
EINECS	Contact for details

Quality Control

Every batch of Adenine-2-D1 is produced and controlled under stringent quality management systems. We provide comprehensive analytical data to ensure the product meets the high standards required for research and development. Certificates of Analysis (COA) detailing isotopic purity, chemical purity, and identity confirmation are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (deuterium, NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.