Description

Adenosine-2-D1 is a stable isotope-labeled analog of adenosine, a fundamental nucleoside in biochemistry. This deuterated compound is essential for advanced research and development, providing a non-radioactive tracer for precise metabolic and pharmacokinetic studies. It is a critical material for scientists in pharmaceutical R&D, analytical chemistry, and life sciences who require high-purity, isotopically labeled standards for mass spectrometry and NMR spectroscopy.

Application

• Internal Standard for LC-MS/MS: Used as a quantitative reference standard in bioanalytical method development for accurate measurement of adenosine and related metabolites in complex biological matrices.
• Metabolic Pathway Tracing: Enables the study of purine metabolism, ATP/ADP cycling, and energy transfer mechanisms in cellular systems without isotopic interference.
• Pharmacokinetic (PK) Studies: Serves as a deuterated tracer to investigate the absorption, distribution, metabolism, and excretion (ADME) of adenosine-based drug candidates.
• NMR Spectroscopy: Provides a valuable tool for structural elucidation and dynamic studies of nucleic acids and enzymatic reaction mechanisms involving adenosine.
• Diagnostic Assay Development: Employed in the calibration and validation of clinical diagnostic kits targeting adenosine-related biomarkers.
• Biochemical Research: Facilitates detailed investigations into receptor-ligand interactions, signal transduction pathways, and the role of adenosine in neurological and cardiovascular functions.

Basic Information

Product Name	Adenosine-2-D1
CAS No.	109923-50-4
Molecular Formula	C10H12D1N5O4
Molecular Weight	268.25 g/mol
Synonyms	2-Deuterioadenosine; Adenosine-2-d; 9-β-D-Ribofuranosyladenine-2-D1; 6-Amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purine-2-D1; Deuterated Adenosine; [2-2H]Adenosine; Adenosine (2-d); Stable Isotope Labeled Adenosine
EINECS	Contact for details

Quality Control

Every batch of Adenosine-2-D1 is manufactured and analyzed under strict quality management protocols. We guarantee high chemical and isotopic purity, supported by comprehensive analytical data including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, isotopic enrichment, and solvent content is provided with each shipment to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term stability, consider storage at -20°C under desiccant.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.